Panangin - instructions for use, indications and contraindications, reviews, price

Active substances: magnesium asparaginate (140 mg) and potassium asparaginate (158 mg).

Additional substances: silicon dioxide, corn and potato starch, talc, povidone, magnesium stearate. The shell consists of talc, macrogol 6000, titanium dioxide, methacrylic acid copolymer.

Pharmachologic effect

What is the cure for? It is a source of potassium, magnesium. The drug helps to restore electrolyte balance, regulates metabolic, metabolic reactions and processes, has a pronounced antiarrhythmic effect. Potassium is actively involved in synaptic transmission, in conducting a nerve impulse through the fibers, in the implementation of muscle contractions, supports the normal functioning of the heart. With impaired potassium metabolism, the excitability of muscle tissue and nerves changes. Thanks to active ion transport, a high gradient of potassium through the plasma membrane is maintained. Small doses of potassium contribute to the expansion of the coronary arteries, and in large doses, the microelement narrows their lumen. Potassium has a moderate diuretic effect, negative batmotropic and chronotropic effects. Magnesium is a cofactor of three hundred serment reactions. Magnesium is an indispensable element in the processes and reactions that ensure the flow, as well as the expenditure of energy. Magnesium enters the pentose phosphate structure of DNA, takes part in the process of cell division and growth, heredity structure, RNA synthesis, is a natural BMCC, prevents the release of free fatty acids, catecholamines under stress, promotes the penetration of potassium ions into the cell. The drug has a stimulating effect on the intercellular synthesis of phosphates.

Mnn: potassium and magnesium asparaginate.

Pharmacological group: potassium and magnesium drug.

Indications for use Panangina

Panangin tablets - what are they from?

Indications for use of Panangin are as follows. The drug is prescribed for hypomagnesemia, hypokalemiawhen taking laxatives and diuretics, glucocorticosteroids, with diarrhea, persistent vomiting, taking saluretics, with myocardial infarction, heart failuredigital intoxication, ventricular extrasystole, atrial extrasystole, supraventricular tachycardia, paroxysmal tachycardia.

Latin recipe example: Rp .: Dragee “Panangin” N. 20

Contraindications to Panangin

The drug is not used for intolerance to fructose, sorbitol, impaired metabolism of amino acids, with chronic pathology of the renal system, hemolysis, exicosis, dehydration, arterial hypotensionmyasthenia gravis, atrioventricular block, hypermagnesemia, hyperkalemia, metabolic acidosisAddison's disease. Panangin is used with caution in pregnancy.

Composition and form of release

The medicine is available in two forms of release - tablets and solution.

The solution for intravenous use is colorless and odorless, in rare cases it can be a greenish transparent color. It is impossible to determine the presence of mechanical impurities in the eye. The preparation contains about 45.2 mg of potassium asparaginate in 1 ml of solution, while the content of K + is 10.33 in the same volume. Also, 1 mg of the solution contains 40 mg of magnesium asparaginate, while the Mg + content is 3.37 mg. The excipient of the solution is distilled water. One ampoule contains 10 ml of a solution intended for intravenous injection. The package of the drug contains 5 ampoules of the drug, packaged in plastic circuits. The packaging of the medicine is cardboard.

The drug, produced in the form of biconvex round tablets, is odorless. The color of the tablets is white or almost white. The tablets are film-coated, making their surface shiny and uneven.

One tablet contains 166.3 mg of potassium asparaginate x 1 / 2H2O, while the content of the potassium asparaginate is 158 mg. Magnesium asparaginate x 4H2O in one tablet contains 175 mg, this corresponds to the content of 140 mg magnesium asparaginate in the tablet. Also, the tablet contains auxiliary substances:

  • corn starch,
  • talc,
  • potato starch,
  • magnesium stearate,
  • povidone
  • silicon dioxide colloidal.

The film coating consists of talc, macrogol 6000, methacrylic acid copolymer (E 100%) and titanium dioxide (col. Ind. 77891, E171). The drug in the form of tablets is available in polypropylene bottles, packed in cardboard boxes. In one bottle - 50 tablets.

Side effects

Side effects are the following manifestations: ulceration of the mucous wall of the digestive tract, epigastric pain, diarrhea, bleeding from the digestive system, drop in blood pressure, bradycardia, a paradoxical reaction in the form of an increase in the number of extrasystoles, dry mouth, nausea, flatulence, hyporeflexia, itchy skin, dyspnea, thrombosis, phlebitis, paresthesia, dizziness, increased sweating, astheniamyasthenia gravis. With rapid intravenous infusion, hypermagnesemia, hyperkalemia are noted.

Instructions for use intravenously

The Panangin solution is administered intravenously, slowly. The drug is administered at a rate of 20-30 drops per minute, 1-2 times a day, 300 ml each. Dosing of the drug Panangin during pregnancy is carried out according to the standard regimen for the use of the drug.

Children can take medicine from birth.

Analogs to the drug Panangin

What is the difference between panangin and asparkam, aspangin - domestic analogues? Panangin is an original drug, more refined. Asparkam is the analogue (copy) of this medicine. The tablets of the drug, coated with a protective coating, protect the gastrointestinal tract from the negative effects, so people suffering from colitis, ulcers and gastritis should be preferred.

The price indications of the drugs also differ: being a copy, aspartame and aspangin are two to three times cheaper than the original at a cost. Most people who have indications for the use of drugs that compensate for the deficiency of K, Mg prefer panangin because of the noticeable effect on the heart muscle, leg muscles, and a decrease in the manifestations of varicose veins.

How to take Panangin for prevention?

If you wonder about the benefits and harms of Panangin, you should realize that this is a drug that has its side effects, so you should not use it for prevention. Firstly, in this way you accustom the body to a high content of magnesium and potassium, and secondly, you can provoke an overabundance of these substances, which in turn can cause a lot of negative reactions.

Pharmacological properties

Panangin tablets, what do they help from? The medicine is a valuable source of potassium and magnesium, normalizes metabolic processes in the body. These substances affect the functioning of the heart and other organs of man. Magnesium and potassium are involved in many enzymes. They are responsible for muscle contraction. Micronutrients are of great importance for the work of the heart muscle.

With a prolonged deficiency of ions, metabolic changes in the myocardium develop, arteriosclerosis of arteries and hypertension may occur. With potassium deficiency, the toxicity of heart glycosides increases, tachycardia and arrhythmia develop. For the reproduction of proteins and nucleic acids, magnesium is responsible. He takes part in most energy metabolic processes.

Thanks to it, the frequency of contractions and the tension of the heart muscle are reduced. The ion has an anti-ischemic effect on the structures of the myocardium. Potassium and magnesium are interconnected, therefore both are present in the Panangin medicine. Typically, the body lacks both substances. With the joint correction of ions, the toxicity of cardiac glycosides decreases, and an inotropic and additive effect is manifested.

Who is prescribed the drug

For those who do not know what Panangin tablets are for, it is worth saying that they are prescribed to compensate for the deficiency of magnesium and potassium, provided they are low in diet.

Less commonly, the tablet form of the drug can be recommended for patients as part of the complex treatment of arrhythmia, heart failure and acute myocardial infarction. In most cases, people with such diseases are prescribed Panangin medicine in the form of a solution for iv administration.

A Panangin solution or tablets are prescribed (the instructions also contain this information) for people suffering from various heart diseases. This is due to the fact that potassium and magnesium ions improve the tolerance of cardiac glycosides.

Panangin tablets: what they help from

Indications for the use of the medication include the following diseases and conditions:

  • hypokalemia
  • myocardial infarction
  • hypomagnesemia,
  • heart failure
  • diarrhea
  • prolonged vomiting
  • paroxysmal tachycardia,
  • digital intoxication,
  • supraventricular tachycardia,
  • atrial and ventricular extrasystole.

The medicine is prescribed when taking glucocorticosteroid drugs, laxative and diuretics. The Latin recipe is as follows: "Rp .: Dragee" Panangin "N. 20."

Overdose

Manifested muscle hypotensionhyperkalemia, slowdown atrioventricular conductionheart failure arrhythmia, paresthesia of the extremities, changes in the electrocardiogram. Emergency intravenous infusion of a solution of dextrose, sodium chloride is required. If necessary, peritoneal dialysis, hemodialysis is justified.

Interaction

Panagin is able to enhance the negative bathmotropic, dromotropic effects antiarrhythmic drugs. The medication eliminates hypokalemia, which develops against the background of prolonged use of diuretics, glucocorticosteroids, and ISS. NSAIDs, ACE inhibitors, heparin, potassium-sparing diuretics, cyclosporine, beta-blockers increase the risk of hyperkalemia. When using general anesthetics, the inhibitory effect of panangin on the nervous system is enhanced. Succinyl chloride, decametonium, atracuronium, suxamethonium enhance neuromuscular blockade. The use of enveloping and astringent medicines reduces the absorption of potassium and magnesium in the digestive tract. In combination with insulin, dextrose in the composition of the polarizing mixture, heart rate normalizes with an overdose of cardiac glycosides, with ectopic arrhythmias, myocardial infarction. Panangin improves tolerance cardiac glycosides, pharmaceutically compatible with their solutions.

7 Analogs of a means

Popular analogues of Panangin are Asparkam, potassium and magnesium asparaginate. These funds are similar in effect, property and a number of side effects on the human body. A group of similar drugs include Aspangin, Pamaton. Each drug has features, so you can not replace one yourself with another.

A popular analogue of Panangin is Asparkam, which is familiar to many patients. Its release was started many years ago and for a long period of time had no corresponding analogues. Russian Asparkam has an identical composition with Panangin, but costs much cheaper. However, not all so simple. Experts say that Asparkam acts worse for the heart than Panangin.

It is important to store Panangin properly. It is necessary to keep it at a temperature not exceeding 30 ° C

The shelf life established by the manufacturer does not exceed 5 years, and for liquid form - 3 years. Children should not be allowed to accidentally use the medicine. Consultation with a specialist is required.

Despite the fact that you can buy Panangin without a prescription, self-administration is undesirable. This is due to the fact that a person may not be aware that he has an individual intolerance or contraindications for the use of this drug.

Panangin is a medicine, it does not belong to the category of vitamins or dietary supplements, so you can not drink it just like that. In order to maintain good health, you need to regularly visit a doctor and undergo an annual medical examination. Do not neglect the safety rules and the prevention of cardiovascular disease.

The cost of the drug varies depending on the pharmacy and the region of the country, but it does not exceed 200 rubles. The price of tablets and injections is different, this is due to the form of release and production technology. The injections are stronger and the tablets less aggressive in the treatment. Therapy and the right drugs are selected by the attending physician. If necessary, you can replace Panangin with analogues, generics. For example, this is done in case of allergies or intolerance to the components of the product.

Release form, composition and packaging

◊ Tablets, film-coated, white or almost white, round, biconvex, with a slightly shiny and uneven surface, almost odorless.

1 tab
potassium asparaginate158 mg
in the form of potassium asparaginate hemihydrate166.3 mg
magnesium asparaginate140 mg
in the form of magnesium asparaginate tetrahydrate175 mg

Excipients: colloidal silicon dioxide, povidone K30, magnesium stearate, talc, corn starch, potato starch.

Shell composition: macrogol 6000, titanium dioxide (E171), butyl methacrylate, dimethylaminoethyl methacrylate and methyl methacrylate copolymer 1: 2: 1, talc.

25 pcs. - blisters (2) - packs of cardboard.
50 pcs. - polypropylene bottles (1) with a first opening control - cardboard packs.

Drug interaction

  • In combination with ACE inhibitors, potassium-sparing diuretics, cyclosporine, beta-blockers, NSAIDs, heparin, the risk of developing hyperkalemia increases.
  • In combination with glucocorticosteroids, hypokalemia is eliminated, which is a side effect of hormone therapy.
  • In combination with cardiac glycosides, their toxicity is reduced.
  • When taken together with antiarrhythmic drugs, their negative dromo- and batmotropic effects are enhanced.
  • Decreased effects of neomycin, tetracycline, polymyxin B and streptomycin.
  • Calcium reduces the effect of magnesium in the composition of Panangin.
  • When used with anesthetics, the inhibitory effect of magnesium on the central nervous system is enhanced.
  • Atracuria, Dexamethonium and Suxamethonium can lead to increased neuromuscular blockade.
  • Calcitroiol increases the level of magnesium in blood plasma.
  • Astringents and enveloping drugs reduce the absorption of Panangin from the digestive tract.

How does it work

Panangin contributes to the proper functioning of many systems.

Potassium and magnesium, which are contained in this medicine, have the following effects on the body:

  • restoration of electrolyte balance,
  • improved myocardial metabolism,
  • antiarrhythmic effect,
  • help in maintaining normal cardiac activity.

Somehow, many people are deficient in these elements. The greater the shortage, the higher the risk of developing hypertension, atherosclerosis, and myocardial changes.

The effect of the drug supplement occurs within a few weeks after the start of use. A person begins to feel better and gets rid of pains in the heart.

The work of the whole organism as a whole is significantly improved.Many systems are bouncing back.

Pharmacokinetics

The total supply of magnesium in the human body weighing 70 kg is an average of 24 g (1000 mmol), more than 60% of the magnesium is in bone tissue and about 40% in skeletal muscle and other tissues. About 1% of the total magnesium supply in the body is in the extracellular fluid, mainly in blood serum. In healthy adults, the serum magnesium content is in the range of 0.7-1.10 mmol / L.

Magnesium is absorbed from the digestive tract by active transport. The main regulator of the balance of magnesium in the body are the kidneys. 3-5% of ionized magnesium is excreted by the kidneys.

An increase in urine volume (for example, during therapy with loop diuretics) leads to an increase in the excretion of ionized magnesium. If the absorption of magnesium in the small intestine decreases, subsequent hypomagnesemia leads to a decrease in its excretion (Potassium

The total supply of potassium in the human body weighing 70 kg is an average of 140 g (3570 mmol). The total potassium supply is slightly less in women than in men, and slightly decreases with age. 2% of the total potassium in the body is outside the cells, and the remaining 98% is inside the cells.

Potassium is absorbed in the digestive tract. The optimal rate of potassium intake with food is 3-4 g (75-100 mmol) / day. The main route of potassium excretion is through the kidneys (about 90% of potassium is excreted by the kidneys daily). The remaining 10% is excreted through the digestive tract. Thus, the kidneys are responsible for long-term potassium homeostasis, as well as for the content of potassium in the blood plasma. In the short term, the potassium content in the blood is also regulated by the flow of potassium between the intracellular and extracellular spaces.

Instructions for use of Panangin in ampoules

The dosage and method of administration must be prescribed by a doctor. Perhaps, it is enough for someone to take pills, but with injections, magnesium and potassium will be better absorbed, and the result will manifest itself faster. Therefore, “Panangin” is administered intravenously, so that the active substances enter immediately into the blood. To do this, dilute the contents of 1 ampoule of the drug with 50 ml of 5% glucose solution. Injection is done by the drip method so that the drug enters the bloodstream gradually (not faster than 20 drops per minute). Otherwise, the risk of side effects increases. You can repeat the dropper after 4-6 hours. Usually, 1-2 Panangin ampoules are administered at a time.

Panangin medicine

The basis of the drug are 2 trace elements - magnesium and potassium ions. Due to them, the medicine normalizes the heart rhythm, further improving the conduction of the nerve impulse along the conduction system of the heart. Restoring ion levels by eliminating magnesium and potassium deficiency helps with heart rhythm disturbances. Such effects help in the treatment or prevention of atherosclerosis, myocardial infarction. Panangin - instructions for its use indicate that it is part of combination therapy against the occurrence of arrhythmias or chronic heart diseases.

Side effects

The Panangin medicine, patient reviews and instructions indicate this, as a rule, is well tolerated by the body. However, side effects can still be observed. Tablets cause:

  • symptoms of hyperkalemia (vomiting, diarrhea, paresthesia, nausea),
  • signs of hypermagnesemia (thirst, cramps, decreased pressure, redness of the face, respiratory depression),
  • atrioventricular block
  • a paradoxical reaction
  • discomfort in the epigastric region.

Injections can provoke with a quick injection of a solution:

  • phlebitis,
  • pressure drop
  • a paradoxical reaction
  • hyperkalemia
  • flushing of the skin,
  • hypermagnesemia.

Dosage

Before use, the patient should consult a doctor.

Inside, without chewing and drinking plenty of water. The drug should be used after meals, as the acidic environment of the stomach reduces its effectiveness.

The usual daily dose is 1-2 tablets. 3 times / day The maximum daily dose is 2 tablets. 3 times / day

The duration of the drug and the need for repeated courses are determined by the doctor.

There are no data on the safety and effectiveness of the use of Panangin in children and adolescents.

Opinions of patients and doctors

About the drug "Panangin" reviews are mostly positive. Patients indicate a good result after undergoing treatment. The tool improves the functioning of the myocardium, relieves cramps. The reviews confirm that Panangin is really good pills for the heart.

They can be used during pregnancy, while doctors point to a good effect. The medicine, if necessary, is prescribed to children from any age. A cheaper analogue of the drug is Asparkam, which has a similar composition and mechanism of action.

Doctors indicate poor compatibility of the drug with alcohol. Firstly, for heart problems drinking alcohol is not recommended. Secondly, alcohol and Panangin can cause spasms of blood vessels. Sometimes pills are taken with a hangover, they make up for the potassium and magnesium necessary for the body in this state.

Tablets and Panangin solution - instructions for use

The drug is available in the form of tablets, it is recommended to take 3 times a day for 1-2 tablets. In this case, the maximum daily dose is 3 doses of 3 tablets. It is recommended to take the medicine only after eating, since the acidic environment of the stomach significantly reduces the effectiveness of the tablets. The duration of the course is determined by the doctor, if necessary, an additional course of treatment can be prescribed.

The injection solution is administered intravenously by slow infusion. The maximum possible dosage in one dose is 2 ampoules, repeated use of the drug is possible only after 4-6 hours. A solution is used for infusion - the contents of 1-2 ampoules of the drug are dissolved in 50-100 ml of a 5% glucose solution.

Pharmacodynamics and pharmacokinetics

Magnesium and potassium are very important for the formation of bonds between macromolecules and intracellular structures, preservation of myocardial function, muscle contraction. Substances help:

  • restore electrolyte balance,
  • regulate metabolic processes and reactions,
  • inhibit the development of arrhythmias due to low levels of potassium and magnesium.

Potassium is an integral part of synaptic transmission, the implementation of muscle contractions. Its asparaginate improves conduction of a nerve impulse. Additionally, the trace element has a diuretic effect. Magnesium is part of the reactions and processes responsible for energy expenditure. It promotes the penetration of potassium ions into the cells. A medicine based on them improves myocardial metabolism. According to the instructions for use, the drug is well absorbed and excreted by the kidneys.

Panangin from which the medicine helps

What is the mechanism of action of panangin when the patient has indications for the use of the drug? The trace elements necessary for the normal activity of the cardiovascular system perform the following functions:

  1. Stimulate the work of the myocardium, increasing the cardiac conduction of impulses.
  2. Strengthen the walls of blood vessels, reducing muscle tone, increasing blood flow.
  3. Normalize heart rate.
  4. Participate in the metabolic processes of the heart, relieve swelling, spasms of the internal organs.

For preventive purposes, cardiologists prescribe panangin to use for patients:

  • with the threat of ischemia,
  • after heart attacks,
  • people suffering from heart pain, swelling,
  • with heart failure, arrhythmias,
  • high blood pressure, hypertension.

Indications for the use of panangin are constant cramping, pain in the muscles of the legs. Lack of active substances leads to a “clamped” state of the muscle system and a constant reduction. Intensive physical exertion, mental work, stressful situations are prerequisites for a deficiency of potassium, magnesium. Taking medication in these cases increases efficiency, enhances stress resistance.

The entry of Mg and K into the composition of the drug is due to the simultaneous deficiency of these trace elements in the body. Potassium and magnesium ions in the complex create additive synergism, when each substance exhibits an effect separately, enhancing the action of the "companion". Indications for use of the drug is a decrease in the toxicity of cardiac glycosides, without affecting the positive effect.

Panangin - what is the remedy for?

What is the mechanism of action of panangin when the patient has indications for the use of the drug? The trace elements necessary for the normal activity of the cardiovascular system perform the following functions:

  1. Stimulate the work of the myocardium, increasing the cardiac conduction of impulses.
  2. Strengthen the walls of blood vessels, reducing muscle tone, increasing blood flow.
  3. Normalize heart rate.
  4. Participate in the metabolic processes of the heart, relieve swelling, spasms of the internal organs.

For preventive purposes, cardiologists prescribe panangin to use for patients:

  • with the threat of ischemia,
  • after heart attacks,
  • people suffering from heart pain, swelling,
  • with heart failure, arrhythmias,
  • high blood pressure, hypertension.

Indications for the use of panangin are constant cramping, pain in the muscles of the legs. Lack of active substances leads to a “clamped” state of the muscle system and a constant reduction. Intensive physical exertion, mental work, stressful situations are prerequisites for a deficiency of potassium, magnesium. Taking medication in these cases increases efficiency, enhances stress resistance.

The entry of Mg and K into the composition of the drug is due to the simultaneous deficiency of these trace elements in the body. Potassium and magnesium ions in the complex create additive synergism, when each substance exhibits an effect separately, enhancing the action of the "companion". Indications for use of the drug is a decrease in the toxicity of cardiac glycosides, without affecting the positive effect.

Pananginum: indications for use

The medicine Panangin makes up for the lack of magnesium and potassium. These substances are needed to strengthen and nourish the heart muscle, so the drug is used to treat and prevent heart ailments.

Special instructions

Taking medication in any form produced does not affect the patient's ability to drive a car or engage in work requiring increased attention or special concentration.

When using the drug, caution should be exercised if the patient has a disease accompanied by hyperkalemia. In addition, it is strongly recommended that blood levels of ions be monitored.

Rapid intravenous administration of a drug can lead to flushing of the skin.

Instructions for use of the drug

The tablet (capsule) form has a high absorption, is excreted in the urine. In some cases, doctors determine the indications for the simultaneous use of cardiac glycosides and panangin. An increased burden on the kidneys becomes a contraindication for diseases of the latter. The pharmacokinetics of intravenous injection is unknown.

Description of the drug

The medicine is available in two forms - injection solution and tablets. Both release forms contain two active components: magnesium asparaginate (content -140 mg) and potassium asparaginate (content - 158 mg). In addition, the composition of the drug is supplemented by other components, depending on the form:

  • in tablets - magnesium stearate, talc, silicon dioxide, povidone, corn and potato starch,
  • in concentrate for the manufacture of an internal solution - distilled water.

There is also a tablet form - Panangin Forte, in which the content of active components is doubled.

Drug action

With the help of Panangin in the heart muscle, metabolic processes are normalized. A reduced number of magnesium and potassium ions can lead to the development of a number of pathological processes. This is the occurrence of various kinds of disorders in the myocardium, and the appearance of coronary artery atherosclerosis, and arterial hypertension. Panangin, as a source of K and Mg ions, can prevent the development of these dangerous diseases.

With a lack of potassium, the toxicity of glycosides of the heart muscle increases - arrhythmia and tachycardia occur. Magnesium is responsible for the reproduction of proteins and nucleic acids, thanks to the substance, the tension and frequency of the heart muscle is reduced.

The functioning of Mg and K in the body is interconnected, therefore the body usually simultaneously lacks both elements. With the joint correction of ion deficiency by taking Panangin, myocardial metabolism is significantly improved.

1 General information about the medicine

Pananginum manufacturers produce in several forms: in the form of tablets and solution. The liquid intended for intravenous administration does not have color and odor, a transparent greenish tint is allowed. When looking at the contents in the solution, no grains should be detected. The composition of the drug contains 45.2 mg of potassium asparaginate per 1 ml of liquid.

The drug is packaged in a plastic shell, five ampoules. To reduce the cost of production, cardboard packaging is used. In a drug that is available in the form of tablets, the color ranges from white to white with a tint. All tablets are covered with an enteric film, from which the appearance of the drug is shiny and uneven.

The tablet contains particles of corn starch, talc, potato starch, magnesium stearate, povidone, silicon dioxide. Talc, titanium dioxide, macrogol 6000 are used for film coating of tablets. Tablets are filled into a bottle of 50 pieces and packed in cardboard boxes.

Application for various pathologies (for specific diseases)

The drug has shown excellent properties in the treatment of various diseases. In the first place among them, of course, ischemic heart disease and myocardial infarction. The drug is also used to successfully treat arrhythmias of various origins. Often there are cases when it is necessary to replenish the reserves of magnesium and potassium in the body. Most often this happens after severe infectious diseases, blood transfusion, large losses of fluid by the body, while taking diuretics, various metabolic disorders and deficiency of elements in the daily diet.

Panangin was also used for children, including newborns. The use of the drug contributes to the rapid closure of most open heart defects in newborns, strengthens the heart muscle of the baby. Also, the drug is used to stop the convulsive syndrome, the main reason for which, as a rule, is a deficiency in the body of potassium and magnesium.

Indications for use

Trace elements contained in Panangin are necessary for the proper functioning of blood vessels and the heart and perform such functions:

  • strengthen vascular walls, increase blood flow and lower muscle tone,
  • stimulate myocardial function, improving the conductivity of impulses in the heart,
  • establish processes of cardiac metabolism, eliminate spasms and swelling of the internal organs,
  • normalize the rhythm of the heart.

Indications for the use of the drug are pain and constant cramping in the muscles of the limbs. Such symptoms develop due to a lack of active substances - the muscle system becomes “pinched”, the muscles are constantly contracting. The tablet form of Panangin is indicated for a lack of K and Mg caused by a lack of these components in the daily diet. The medication is included in the complex therapy of various disorders in the work of the heart and myocardial infarction.

Panangin is recommended to drink under intense stress, frequent stressful situations - taking the medicine will increase stress resistance and increase performance.

For prevention, the medicine is prescribed:

  • recent heart attack patients
  • with hypertension, constant high blood pressure,

Panangin is also prescribed for newborns - its use helps to quickly close heart diseases in babies and helps strengthen the baby’s heart muscle. Also, the medication is used to relieve seizures in newborns, which, as a rule, are caused by a lack of K and Mg.

The drug is recommended for all patients over 45 years of age, as well as people trying to lose weight with laxatives or diets, actively involved in sports, taking sedatives and hormones, and medicines for gastrointestinal pathologies. Manufacturers recommend drinking Panangin for almost any abnormalities in the body, but uncontrolled use of the drug can seriously harm the body.

Injection

Acute cases are an indication for the use of a liquid form of panangin. 10 ml of injection is diluted with 20 - 40 ml of isotonic sodium chloride or 5% glucose. The drug is administered by injection very slowly and gradually, so as not to cause signs of hyperkalemia, hypermagnesemia: nausea, vomiting reflexes, dizziness.

For patients with hypersensitivity to potassium, magnesium, doctors prescribe droppers. Two ampoules of the drug are diluted with 0.3 - 0.5 l of saline (0.9% aqueous solution of NaCl) or a five percent solution of dextrose. Then they are administered to the patient drip. The time interval between injections: 4 to 6 hours. Perhaps the use of drugs as part of complex therapy.

Side effects and contraindications

Manufacturers report that the development of negative phenomena is observed with Panangin extremely rarely, but nevertheless, the risk of such effects is not excluded with improper or excessively long use of the medication. When using a medication, intravenous side effects usually develop only when it is administered too quickly - hyperkalemia or hypermagnesemia may occur.

When taking tablets, it is possible to develop:

  • diarrhea
  • paresthesia
  • discomfort in the pancreas,
  • respiratory depression

Especially careful should be applied to the use of the medication for pregnant and lactating women, in whom the advisability of using the medication is discussed with the attending physician. It is forbidden to apply:

    tablets: with dehydration, hemolysis, AV blockade of 1 degree, metabolic acidosis, severe myasthenia gravis, impaired amino acid metabolism,

It is not recommended to use the drug for chronic alcoholism, individual sensitivity to the components, acute heart failure, steadily reduced blood pressure, chronic kidney disease.

Panangin or Asparkam?

The most popular analogue of Panangin is, of course, Asparkam. This medicine is time-tested. It was produced several decades ago. The drug is domestic production, its composition is similar to that of Panangin. Moreover, its cost is many times lower.

However, the main indicator required of a medicine is its effectiveness. Many patients who used both drugs noted the great effectiveness of Panangin.

Contraindications to the use of the drug

The absence of indications for use, the use of panangin are:

  • Heart failure (acute).
  • Chronic kidney disease, acute failure.
  • Intolerance to the components of the drug.
  • Alcoholism.
  • Confusion, fatigue, myasthenia gravis, parasthesia are signs of hyperkalemia.
  • Dehydration.
  • Stably low blood pressure, cases of cardiogenic shock.
  • Low muscle irritability, shortness of breath, dizziness, nausea are symptoms of hypermagnesemia.

Caution, only under the supervision of a doctor is prescribed panangin to patients with pathology of conduction of the heart muscle. A burning sensation, discomfort in the epidural area is the reason for lowering the dosage of the medicine. It is not recommended to use panangin for women in the first trimester of pregnancy when breastfeeding a baby.

Panangin - instructions for use, indications and contraindications, reviews, price

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Specialist consultation required!

The approximate cost of Panangin in tablets and ampoules

It is possible to purchase panangin in ordinary and online pharmacies in Russia. The price of a drug varies by region. So, if you want to buy a drug in Moscow, the cost will be from 120 to 155 rubles. for tablets and about 160 - 165 rubles for a solution for intravenous administration. The average price of panangin is about 130 - 140 rubles. in the form of capsules and 160 - 166 rubles for the packaging of ampoules.

Application Reviews

Anton, Khabarovsk
The composition of the medicine is quite harmless. Therefore, I periodically take panangin for prevention. In addition, it contains a lot of potassium and magnesium. It is very beneficial for the body as a whole.

Natalia, Voskresensk
I have a difficult job, when I get nervous again, arrhythmia begins. My friend is a cardiologist, and she advised me to try Panangin. Most of all I liked the fact that you need to drink the medicine only when it is really necessary. And when the heart does not bother, then you do not need to drink anything.

Marina, Moscow
And I was constantly bothered by the beating of my heart at night, I could not even sleep peacefully. I drank the course of Panagin according to the instructions, everything returned to normal.

Victor, Perm
The doctor prescribed a course of treatment with Panangin for a month, he has not passed yet, but I feel much better. There are almost no attacks of arrhythmia.

Tablets and Panangin solution - instructions for use

The drug is available in the form of tablets, it is recommended to take 3 times a day for 1-2 tablets. In this case, the maximum daily dose is 3 doses of 3 tablets. It is recommended to take the medicine only after eating, since the acidic environment of the stomach significantly reduces the effectiveness of the tablets. The duration of the course is determined by the doctor, if necessary, an additional course of treatment can be prescribed.

The injection solution is administered intravenously by slow infusion. The maximum possible dosage in one dose is 2 ampoules, repeated use of the drug is possible only after 4-6 hours. A solution is used for infusion - the contents of 1-2 ampoules of the drug are dissolved in 50-100 ml of a 5% glucose solution.

Reviews about Panangin

Reviews about Panangin in the forums are mostly positive. Buyers mark the drug as really effective, the medication facilitates the work of the heart, relieves cramps, really helps. Celebrated as good pills for the heart.

Reviews about Panangin during pregnancy are as follows: the medication is often prescribed by doctors and is quite effective, despite the fact that it is recommended to use the drug with caution in this period in the description of the drug.

Storage conditions

Out of the reach of children at a temperature of 15-30 degrees Celsius.

Shelf life

Analogs of Panangin

The substitutes can be considered such analogues of Panangin as Asparkam, Biolectra Magnesium Fortissimum, Potassium and Magnesium Asparaginate.

Alcohol compatibility

The drug is poorly compatible with alcohol, if only because the drug is usually used for problems with the heart and vascular system, and alcohol in these cases should be excluded. However, that is not all. With the simultaneous use of these substances, vasospasm may occur.

Reviews about Panangin

Reviews about Panangin in the forums are mostly positive. Buyers mark the drug as really effective, the medication facilitates the work of the heart, relieves cramps, really helps. Celebrated as good pills for the heart.

Reviews about Panangin during pregnancy are as follows: the medication is often prescribed by doctors and is quite effective, despite the fact that it is recommended to use the drug with caution in this period in the description of the drug.

Panangin price

The price of Panangin in tablets is 130 rubles, the price in ampoules is 160 rubles.

How much do tablets cost in St. Petersburg? You can buy them at a cost of 125 rubles.

The price of Panangin is in Ukraine 120 and 130 UAH per tablet and solution, respectively.

Panangin composition

Composition of the tablets

Active substances: magnesium asparaginate (140 mg) and potassium asparaginate (158 mg).

Additional substances: silicon dioxide, corn and potato starch, talc, povidone, magnesium stearate. The shell consists of talc, macrogol 6000, titanium dioxide, methacrylic acid copolymer.

Concentrate for solution (Panangin iv)

Contains magnesium asparaginate (40 mg) and potassium asparaginate (45.2 mg), as well as water for injection.

Release form

Available in tablet form, and as a solution concentrate.

Pharmachologic effect

What is the cure for? It is a source of potassium, magnesium. The drug helps to restore electrolyte balance, regulates metabolic, metabolic reactions and processes, has a pronounced antiarrhythmic effect. Potassium is actively involved in synaptic transmission, in conducting a nerve impulse through the fibers, in the implementation of muscle contractions, supports the normal functioning of the heart. With impaired potassium metabolism, the excitability of muscle tissue and nerves changes. Thanks to active ion transport, a high gradient of potassium through the plasma membrane is maintained. Small doses of potassium contribute to the expansion of the coronary arteries, and in large doses, the microelement narrows their lumen. Potassium has a moderate diuretic effect, negative batmotropic and chronotropic effects. Magnesium is a cofactor of three hundred serment reactions. Magnesium is an indispensable element in the processes and reactions that ensure the flow, as well as the expenditure of energy. Magnesium enters the pentose phosphate structure of DNA, takes part in the process of cell division and growth, heredity structure, RNA synthesis, is a natural BMCC, prevents the release of free fatty acids, catecholamines under stress, promotes the penetration of potassium ions into the cell. The drug has a stimulating effect on the intercellular synthesis of phosphates.

Mnn: potassium and magnesium asparaginate.

Pharmacological group: potassium and magnesium drug.

Pharmacodynamics and pharmacokinetics

The active substances play an important role in the formation of bonds between macromolecules, as well as intracellular structures and the mechanism of muscle contraction, myocardial metabolism.

According to the annotation, the drug is well absorbed. It is excreted through the kidneys.

Indications for use Panangina

Panangin tablets - what are they from?

Indications for use of Panangin are as follows. The drug is prescribed for hypomagnesemia, hypokalemiawhen taking laxatives and diuretics, glucocorticosteroids, with diarrhea, persistent vomiting, taking saluretics, with myocardial infarction, heart failuredigital intoxication, ventricular extrasystole, atrial extrasystole, supraventricular tachycardia, paroxysmal tachycardia.

Latin recipe example: Rp .: Dragee “Panangin” N. 20

Contraindications to Panangin

The drug is not used for intolerance to fructose, sorbitol, impaired metabolism of amino acids, with chronic pathology of the renal system, hemolysis, exicosis, dehydration, arterial hypotensionmyasthenia gravis, atrioventricular block, hypermagnesemia, hyperkalemia, metabolic acidosisAddison's disease. Panangin is used with caution in pregnancy.

Side effects

Side effects are the following manifestations: ulceration of the mucous wall of the digestive tract, epigastric pain, diarrhea, bleeding from the digestive system, drop in blood pressure, bradycardia, a paradoxical reaction in the form of an increase in the number of extrasystoles, dry mouth, nausea, flatulence, hyporeflexia, itchy skin, dyspnea, thrombosis, phlebitis, paresthesia, dizziness, increased sweating, astheniamyasthenia gravis. With rapid intravenous infusion, hypermagnesemia, hyperkalemia are noted.

Instructions for use Panangina (Method and dosage)

Panangin tablets, instructions for use

How to drink medicine? The drug is taken orally three times a day, 2 tablets. Supportive and preventive therapy: three times a day, 1 tablet, course for 3-4 weeks. In some situations, a repeat course of therapy is required.

Instructions for use intravenously

The Panangin solution is administered intravenously, slowly. The drug is administered at a rate of 20-30 drops per minute, 1-2 times a day, 300 ml each. Dosing of the drug Panangin during pregnancy is carried out according to the standard regimen for the use of the drug.

Children can take medicine from birth.

How to take Panangin for prevention?

If you wonder about the benefits and harms of Panangin, you should realize that this is a drug that has its side effects, so you should not use it for prevention. Firstly, in this way you accustom the body to a high content of magnesium and potassium, and secondly, you can provoke an overabundance of these substances, which in turn can cause a lot of negative reactions.

Overdose

Manifested muscle hypotensionhyperkalemia, slowdown atrioventricular conductionheart failure arrhythmia, paresthesia of the extremities, changes in the electrocardiogram. Emergency intravenous infusion of a solution of dextrose, sodium chloride is required. If necessary, peritoneal dialysis, hemodialysis is justified.

Interaction

Panagin is able to enhance the negative bathmotropic, dromotropic effects antiarrhythmic drugs. The medication eliminates hypokalemia, which develops against the background of prolonged use of diuretics, glucocorticosteroids, and ISS. NSAIDs, ACE inhibitors, heparin, potassium-sparing diuretics, cyclosporine, beta-blockers increase the risk of hyperkalemia. When using general anesthetics, the inhibitory effect of panangin on the nervous system is enhanced. Succinyl chloride, decametonium, atracuronium, suxamethonium enhance neuromuscular blockade. The use of enveloping and astringent medicines reduces the absorption of potassium and magnesium in the digestive tract. In combination with insulin, dextrose in the composition of the polarizing mixture, heart rate normalizes with an overdose of cardiac glycosides, with ectopic arrhythmias, myocardial infarction. Panangin improves tolerance cardiac glycosides, pharmaceutically compatible with their solutions.

Terms of sale

No prescription required.

Storage conditions

Out of the reach of children at a temperature of 15-30 degrees Celsius.

Indications for use of panangin

The health of the body, work, the "interaction" of organs depend on many factors. The most important is the balance of trace elements and minerals. Magnesium and potassium are actively involved in the "debugging" of the activity of blood vessels, heart. Promoting myocardial metabolism, improving the metabolic processes of the heart, they protect a person from heart attacks, arrhythmias, tachycardia and other diseases.The body receives these substances from outside - with food or as a result of taking special medications: asparkama or panangina. What is the last good, what are the indications for use of the panangin medicine?

Watch the video: Panangin Forte - Ответственный за ритм! (February 2020).